Changes in Brain Lipid Composition in Thiamine Deficient Rats

Changes in brain lipid composition in thiamine deficient rats.

Brain lipid composition was studied in thiamine deficient rats treated with thiamine antimetabolites (oxythiamine: OT, and pyrithiamine: PT) and thiamine deficient diet (TDD). After intraperitoneal injection of OT (40 mg/kg/day) or TDD feeding for 6 days, body weight gain decreased. However, the PT (500 micrograms/kg/day) treated rats or the pair fed control (PFC: TDD + thiamine of 5 mg/kg, i.p...

Glyoxalase and methylglyoxal in thiamine-deficient rats.

Thiamine-deficient Diet in Tourniquet Shock in Rats.

Effect of thiamine on serotonin oxidation in magnesium-deficient rats.

To clarify the effect of thiamine on serotonin-related metabolism in magnesium-deficient rats, in vivo and in vitro experiments were carried out. In thiamine-excess magnesium-deficient and thiamine-adequate magnesium-deficient rats, serotonin oxidation activity in liver and stomach decreased significantly, while a decrease was not observed in thiamine-deficient magnesium-deficient rats. In vitr...

Effect of thiamine on lipid profile in diabetic rats.

OBJECTIVE To determine the effect of high dose thiamine on dyslipidemia in diabetic rats. STUDY DESIGN Experimental interventional study. PLACE AND DURATION OF STUDY The Animal House/Laboratory of the National Reference Laboratory for Poultry Diseases (NRLPD)/Biochemistry Department, Army Medical College, Rawalpindi, from December 2006 to January 2007. METHODOLOGY The study was conducted ...